objective: curcumin is extracted from curcuma longa and regulates the intracellular signal pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis. curcumin molecules have special intrinsic features that can target the intracellular enzymes, genome (dna) and messengers (rna). a wide range of studies have been conducted on the physicochemical traits and pharmaco...

Curcumin: Curcumin is a yellow colored compound found in the rhizomes of Curcuma longa (turmeric), a member of the ginger family (Zingiberaceae). Structurally curcumin is a diarylheptanoid, a tautomeric compound, present in keto form in water and enolic form in the organic solvents. The therapeutic efficacy of curcumin is extensively studied against neurodegenerative diseases as it possesses an...

BACKGROUND Curcumin (diferuloylmethane) shows significant activity across a wide spectrum of conditions, but its usefulness is rather limited because of its low bioavailability. Use of nanoparticle formulations to enhance curcumin bioavailability is an emerging area of research. METHODOLOGY/PRINCIPAL FINDINGS In the present study, curcumin-loaded apotransferrin nanoparticles (nano-curcumin) p...

Curcumin, a poorly water-soluble bioactive compound, was successfully loaded into three different aromatic contents of hydroxypropylmethacrylamide (HPMA)-based polymeric micelles in order to develop water-soluble curcumin nanoformulations (Cur-Nano). The stability study of Cur-Nano was done by keeping the formulations at 4, 30, and 40 °C for 90 days. The physical appearance, curcumin remaining,...

Objective: Curcumin is extracted from Curcuma longa and regulates the intracellular signal pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis. Curcumin molecules have special intrinsic features that can target the intracellular enzymes, genome (DNA) and messengers (RNA). A wide range of studies have been conducted on the physicochemical traits and pharmaco...

Pancreatic cancer is currently one of the most deadly types of cancer. Poor patient prognosis is linked to the lack of effective early detection techniques and emerging resistance to current therapeutic strategies. Thus, current research efforts are focusing on overcoming drug resistance. One branch of this field of study is the use of natural compounds to combat pancreatic cancer and drug resi...

The recent development of several methods for extracting curcumin from the root plant Curcuma longa has led to intensified research on properties and its fields application. Following studies accreditation as a natural compound with antifungal, antiviral, antibacterial properties, new application have been developed in two main directions—food medical, respectively. This review paper aims synth...

Background: In recent years, nanotechnology with modern advances in the macromolecular design of nano-carriers has proved to be helpful in the development of drugs delivery systems. This research represents a novel co-administration of nano-vehicles, known as liposomes. Liposomes efficiently encapsulate curcumin and bromocriptine (BR) in a polymer structure, which results in enhanced aqueous so...

OBJECTIVE Curcumin is extracted from Curcuma longa and regulates the intracellular signal pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis. Curcumin molecules have special intrinsic features that can target the intracellular enzymes, genome (DNA) and messengers (RNA). A wide range of studies have been conducted on the physicochemical traits and pharmacol...